
This take on Sir Arthur Conan Doyle's classic character has Sherlock Holmes fleeing London for present-day Manhattan after a stint in rehab. He arrives to find that his father has assigned a sober companion to live with him -- Dr. Joan Watson, a former surgeon who gave up medicine three years earlier after she lost a patient. Her life now centers around helping addicts stay clean. However, Holmes has his own plan for keeping on the straight and narrow, throwing himself into his work as a police consultant in New York City. The two find that they make a good team and are soon cracking some of the NYPD's most-difficult cases.

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Holmes and Watson investigate the death of a wealthy businessman who a witness claims was chased down by a large, glowing animal; Sherlock believes ME Hawes' work may be compromised because of the trauma caused by the morgue bombing.
When a vigilante dressed as a comic book hero is murdered, it's up to Holmes and Watson to find the man's true identity and locate his killer; Morland tries to charm Watson into doing him a favor.
Holmes and Watson must determine whether a survival doctor is a victim of foul play or has purposely gone into hiding; Holmes behaves oddly when his relationship with Fiona reaches a crucial point.
A woman claiming to be a former associate of Sherlock's brother tells Holmes and Watson her life is in danger.