
Perhaps their strikingly different personalities make the relationship between detective Jane Rizzoli and medical examiner Maura Isles so effective. Jane, the only female cop in Boston's homicide division, is tough, relentless and rarely lets her guard down, while the impeccably dressed Maura displays a sometimes icy temperament -- she is, after all, more comfortable among the dead than the living. Together, the best friends have forged a quirky and supportive relationship; they drop the protective shield in each other's company, and combine their expertise to solve Boston's most complex cases.

The squad works overtime hunting down a serial killer; Maura befriends a witness to the crime who suffers from a medical condition that causes him to believe he is a wolf.

Jane and the team try to find the contamination source after a man dies from poisoning; Stanley's true feelings are revealed; Tommy and Lydia disagree about custody of their baby; Detective Korsak reunites with his ex-wife.

After a woman discovers that her husband has been murdered, the investigation reveals that the victim may have been living a double life.

A famous author's suicide might not be all that it seems; Frost reviews an old murder case; Jane discovers Angela's new romance.